Structure of PDB 6kiw Chain A

Receptor sequence
>6kiwA (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6kiw Structural basis of nucleosome recognition and modification by MLL methyltransferases.
ChainA
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R42 T45 R72 R83 F84 M120 R5 T8 R35 R46 F47 M83
BS02 dna A R40 Y41 P43 V46 R49 R3 Y4 P6 V9 R12
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6kiw, PDBe:6kiw, PDBj:6kiw
PDBsum6kiw
PubMed31485071
UniProtP84233|H32_XENLA Histone H3.2

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