Structure of PDB 6kik Chain A

Receptor sequence
>6kikA (length=275) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
SMLYKELGRTGEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGY
THIDTAEYYGGGHTEELIGKAIKDFRREDLFIVSKVWPTHLRRDDLLRSL
ENTLKRLDTDYVDLYLIHWPNPEIPLEETLSAMAEGVRQGLIRYIGVSNF
DRRLLEEAISKSQEPIVCDQVKYNIEDRDPERDGLLEFCQKNGVTLVAYS
PLRRTLLSEKTKRTLEEIAKNHGATIYQIMLAWLLAKPNVVAIPKAGRVE
HLRENLKATEIKLSEEEMKLLDSLG
3D structure
PDB6kik Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
ChainA
Resolution1.601 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TOL A W21 E27 Y57 Y58 K84 H117 W22 E28 Y58 Y59 K85 H118
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6kik, PDBe:6kik, PDBj:6kik
PDBsum6kik
PubMed31573681
UniProtQ9X265

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