Structure of PDB 6kfz Chain A

Receptor sequence
>6kfzA (length=406) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
HMNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYN
SNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMV
ALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGT
ISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDG
AQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEF
GGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEI
SRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLD
AEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTK
EYFTNV
3D structure
PDB6kfz Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
ChainA
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C6P A A28 A29 T92 T93 H121 N173 D198 A200 Q201 S221 H223 K224 R356 R376 A29 A30 T93 T94 H122 N174 D199 A201 Q202 S222 H224 K225 R357 R377
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0006534 cysteine metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6kfz, PDBe:6kfz, PDBj:6kfz
PDBsum6kfz
PubMed31587510
UniProtO32164|SUFS_BACSU Cysteine desulfurase SufS (Gene Name=sufS)

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