Structure of PDB 6kf9 Chain A

Receptor sequence
>6kf9A (length=900) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
KKVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVI
DPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECG
RIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQ
FPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLH
PEKSRPEWMVLTVLPVPPVTMRPSITLESGIRAEDDLTHKLVDIIRINNR
LKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTL
AQRLKGKEGRFRGNLSGKRVNFSARTVISPDPMISINEVGVPLAVAMELT
VPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAE
KLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPV
CPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGI
QDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWS
GKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIEEKLIPDPEEVRKLA
YDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVT
KLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRG
ELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTG
ARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFV
TNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKV
DYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRTLLKMRGG
3D structure
PDB6kf9 Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
ChainA
Resolution3.79 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q427 T835 Y840 Q423 T831 Y836
BS02 MG A D461 D465 D457 D461
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6kf9, PDBe:6kf9, PDBj:6kf9
PDBsum6kf9
PubMed33257704
UniProtQ5JE33

[Back to BioLiP]