Structure of PDB 6kdv Chain A

Receptor sequence
>6kdvA (length=263) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
LPKFRDGLSYLYVEHAVVEREAGGIGIYDQEGLTLAPVAGLGVLFLGPGT
RITHAAVRLLAENGCTVAWVGEGMARFYAQGLGDTRSAARFYRQARAWAD
PALHLEVVMRLYRMRFPEGLTLEQVRGLEGVRVRNAYARWSRETGVPWYG
RSYDRGNWRAADPVNRALSAGASYLYGLAHAAIVSLGFSPALGFIHTGKL
LSFVYDIADLYKADYLVPAAFRTVAESEEAVERRVRRALREAIQEGRLLE
RMAEDLLNLFRGL
3D structure
PDB6kdv Crystal structure of Cas1 in complex with branched DNA.
ChainA
Resolution3.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H27 E84 R88 Y90 Y124 R142 G146 Y153 R167 S168 Y169 R171 W174 S185 Y192 H212 Y221 R252 H15 E72 R76 Y78 Y112 R126 G130 Y137 R151 S152 Y153 R155 W158 S169 Y176 H196 Y205 R236
BS02 dna A H27 A28 E31 Y40 D41 Q42 G61 R63 H15 A16 E19 Y28 D29 Q30 G49 R51
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6kdv, PDBe:6kdv, PDBj:6kdv
PDBsum6kdv
PubMed31792780
UniProtQ53WG8|CAS1B_THET8 CRISPR-associated endonuclease Cas1 2 (Gene Name=cas1-2)

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