Structure of PDB 6kc4 Chain A

Receptor sequence
>6kc4A (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
SKPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQ
RRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIP
K
3D structure
PDB6kc4 High-resolution structural analysis shows how different crystallographic environments can induce alternative modes of binding of a phosphotyrosine peptide to the SH2 domain of Fer tyrosine kinase.
ChainA
Resolution1.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R467 R483 S485 H486 G487 K488 V493 R503 H504 F505 I506 R16 R32 S34 H35 G36 K37 V42 R52 H53 F54 I55
External links
PDB RCSB:6kc4, PDBe:6kc4, PDBj:6kc4
PDBsum6kc4
PubMed31441171
UniProtP16591|FER_HUMAN Tyrosine-protein kinase Fer (Gene Name=FER)

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