Structure of PDB 6kbn Chain A

Receptor sequence
>6kbnA (length=498) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQVSREVLEPILILLQS
QDPQIQVAACAALGNLAVNNENKLLIVEMGGLEPLINQMMGDNVEVQCNA
VGCITNLATRDDNKHKIATSGALIPLTKLAKSKHIRVQRNATGALLNMTH
SEENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA
QTEPRLVSKLVSLMDSPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPH
LVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRLLDYKD
SEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDSPVSVQSEI
SACFAILALADVSKLDLLEANILDALIPMTFSQNQEVSGNAAAALANLCS
RVNNYTKIIEAWDRPNEGIRGFLIRFLKSDYATFEHIALWTILQLLESHN
DKVEDLVKNDDDIINGVRKMADVTFERLQRSGDASLELYNITQQILQF
3D structure
PDB6kbn Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways.
ChainA
Resolution3.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G110 N111 V114 N145 G148 N152 N186 L192 N193 Y226 Y227 N234 V237 R276 N277 R317 E348 E349 C352 H353 S391 S394 E395 N436 G64 N65 V68 N99 G102 N106 N140 L146 N147 Y180 Y181 N188 V191 R230 N231 R271 E302 E303 C306 H307 S345 S348 E349 N390
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0043495 protein-membrane adaptor activity
Biological Process
GO:0000011 vacuole inheritance
GO:0000045 autophagosome assembly
GO:0000425 pexophagy
GO:0006629 lipid metabolic process
GO:0006914 autophagy
GO:0016236 macroautophagy
GO:0031503 protein-containing complex localization
GO:0034497 protein localization to phagophore assembly site
GO:0034517 ribophagy
GO:0034727 piecemeal microautophagy of the nucleus
GO:0042144 vacuole fusion, non-autophagic
GO:0051656 establishment of organelle localization
GO:0071255 Cvt vesicle assembly
GO:0071562 nucleus-vacuole junction assembly
GO:1903044 protein localization to membrane raft
Cellular Component
GO:0000329 fungal-type vacuole membrane
GO:0000407 phagophore assembly site
GO:0005640 nuclear outer membrane
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0005829 cytosol
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0045121 membrane raft
GO:0071561 nucleus-vacuole junction
GO:0071563 Myo2p-Vac17p-Vac8p transport complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6kbn, PDBe:6kbn, PDBj:6kbn
PDBsum6kbn
PubMed31512555
UniProtP39968|VAC8_YEAST Vacuolar protein 8 (Gene Name=VAC8)

[Back to BioLiP]