Structure of PDB 6k9m Chain A

Receptor sequence
>6k9mA (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
QLTAAQELMIQQLVAAQLQCNKRSFSDPKVTPWPSASQQRFAHFTELAII
SVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECI
TFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAIN
IFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVS
LRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHKILHRLLQD
3D structure
PDB6k9m Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 D43 A F271 A275 M312 F329 Y335 H435 F44 A48 M85 F102 Y108 H208
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006629 lipid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6k9m, PDBe:6k9m, PDBj:6k9m
PDBsum6k9m
PubMed32961480
UniProtP55055|NR1H2_HUMAN Oxysterols receptor LXR-beta (Gene Name=NR1H2)

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