Structure of PDB 6k5o Chain A

Receptor sequence
>6k5oA (length=237) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRPLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSW
DCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAI
CIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQK
LADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFG
3D structure
PDB6k5o Development of novel lithocholic acid derivatives as vitamin D receptor agonists.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 Q255 I256 K260 P412 E416 I56 K60 Q73 I74 K78 P230 E234
BS02 D0O A Y143 S271 S274 W282 Y21 S89 S92 W100
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6k5o, PDBe:6k5o, PDBj:6k5o
PDBsum6k5o
PubMed31300316
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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