Structure of PDB 6k3j Chain A

Receptor sequence
>6k3jA (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
MDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQA
PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMA
KFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHC
WDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
3D structure
PDB6k3j Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
ChainA
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.5.4.38: single-stranded DNA cytosine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A N208 E209 V212 G214 R215 H216 T218 N244 Q245 A246 H248 L253 R256 W285 R313 Y315 E366 H367 D370 N12 E13 V16 G18 R19 H20 T22 N48 Q49 A50 H52 L57 R60 W89 R117 Y119 E170 H171 D174
BS02 ZN A H257 C288 C291 H61 C92 C95
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:6k3j, PDBe:6k3j, PDBj:6k3j
PDBsum6k3j
PubMed31116511
UniProtQ9HC16|ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G (Gene Name=APOBEC3G)

[Back to BioLiP]