Structure of PDB 6jxu Chain A

Receptor sequence
>6jxuA (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
YIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQR
IADNHTPKELGMEEEDVIEVYQEQTGG
3D structure
PDB6jxu The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S31 S32 E33 H35 F36 K37 T42 L47 R54 S11 S12 E13 H15 F16 K17 T22 L27 R34
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0015459 potassium channel regulator activity
GO:0019899 enzyme binding
GO:0031386 protein tag activity
GO:0031625 ubiquitin protein ligase binding
GO:0044388 small protein activating enzyme binding
GO:0044389 ubiquitin-like protein ligase binding
GO:1990381 ubiquitin-specific protease binding
Biological Process
GO:0006281 DNA repair
GO:0006355 regulation of DNA-templated transcription
GO:0010621 negative regulation of transcription by transcription factor localization
GO:0016925 protein sumoylation
GO:0030578 PML body organization
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031647 regulation of protein stability
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032880 regulation of protein localization
GO:0034605 cellular response to heat
GO:0042308 negative regulation of protein import into nucleus
GO:0043392 negative regulation of DNA binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045759 negative regulation of action potential
GO:0045892 negative regulation of DNA-templated transcription
GO:0050821 protein stabilization
GO:0060021 roof of mouth development
GO:0071276 cellular response to cadmium ion
GO:0086004 regulation of cardiac muscle cell contraction
GO:0090204 protein localization to nuclear pore
GO:1901896 positive regulation of ATPase-coupled calcium transmembrane transporter activity
GO:1902260 negative regulation of delayed rectifier potassium channel activity
GO:1903169 regulation of calcium ion transmembrane transport
Cellular Component
GO:0001741 XY body
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016604 nuclear body
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0031965 nuclear membrane
GO:0097165 nuclear stress granule
GO:0098978 glutamatergic synapse
GO:0099523 presynaptic cytosol
GO:0099524 postsynaptic cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6jxu, PDBe:6jxu, PDBj:6jxu
PDBsum6jxu
PubMed32001251
UniProtP63165|SUMO1_HUMAN Small ubiquitin-related modifier 1 (Gene Name=SUMO1)

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