Structure of PDB 6jxd Chain A

Receptor sequence
>6jxdA (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB6jxd PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y41 R42 T45 R72 R83 F84 Q85 S86 R116 T118 M120 Y4 R5 T8 R35 R46 F47 Q48 S49 R79 T81 M83
BS02 dna A H39 R40 Y41 G44 V46 A47 R49 R63 K64 L65 R69 R83 H2 R3 Y4 G7 V9 A10 R12 R26 K27 L28 R32 R46
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6jxd, PDBe:6jxd, PDBj:6jxd
PDBsum6jxd
PubMed31848352
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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