Structure of PDB 6ju5 Chain A

Receptor sequence
>6ju5A (length=542) Species: 5062 (Aspergillus oryzae) [Search protein sequence]
SPYLITGIPKDPKHPLPIRKDIDDWYLEQTSAGSNRIQLTLFVEALTVIQ
NRPLNDQLSYFRLAGIHGAPWTEWDGVPGTGFAVHNNYTFPTWHRVYVTL
YEQVIYEAMLDFIKQNVPQNGKADWENEAKQWRLPYWDFARFARDELRLP
ILVTMPMVKVLVPGQPGKQLSKPNPLYRFQMQTLMGTLERPYAITSFDLP
FDKCQSTTKYGLLENYNADVWADGGQNWLRANLALNEHPWYQNLDGWDSV
PTLQDMTFRLLTTGGLNWGEFSSTRYDDAPKNWMNLEAIHNNVHNWVGGF
MFSRPGRHDLKLWGAGHMSSVPVAAYDPIFWLHHCNIDRLTAIWQTVNSG
SWFNDDKSKVSKDDDLRPFHRFCEKTRKVVFFRSDDVKDWRSLNYDYAIT
KDASRIRKEISDLYGEDYILSIRYSRYALGGKPFQINIFFGDVDGKDFYD
ARSQNFVGSVFNYSGAQQEQEGVLSVSQLPARLAVHYYKKQNKGEVPTPR
YVVVNSQGKAEAEVKVEVALHKTDYRRVADGKRAEVDDAYRA
3D structure
PDB6ju5 Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
ChainA
Resolution1.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.18.1: tyrosinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A H67 H94 H103 H67 H85 H94
BS02 CU A H328 H332 H372 H290 H294 H334
Gene Ontology
Molecular Function
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ju5, PDBe:6ju5, PDBj:6ju5
PDBsum6ju5
PubMed32356371
UniProtA0A1S9DK56

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