Structure of PDB 6jon Chain A

Receptor sequence
>6jonA (length=280) Species: 1230469 (Nitratiruptor phage NrS-1) [Search protein sequence]
HMIMEIPAIKALSRYAQWVIWKKERDTKIPYNPNNGKKASSTDPLAWGDI
DEAQAGLVRYGANGLGFVLTKSDPFVFIDLDHVLDENKRVKCEWARQLLK
EIKSYTEISPSGDGLHVVVSGKLPDYIKHKTKFDDGSALEVYESGRYMTI
TGEVFDGRDDIKELDLSILGEFAEHKILDDEAIIDLMKRKGQWPDAPKDG
DDWSSLDMSFANRLAFWCGKDIERMDRIFRQSPLMRQKWDRPTAGSTYGR
ITLKKACDFVDSVYDPALRNESDCPFEPYN
3D structure
PDB6jon Crystal structures of phage NrS-1 N300-dNTPs-Mg2+complex provide molecular mechanisms for substrate specificity.
ChainA
Resolution2.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.7: DNA-directed DNA polymerase.
3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DTP A K27 D78 D80 S108 P109 S110 H115 R145 Y146 M147 T148 K28 D79 D81 S109 P110 S111 H116 R146 Y147 M148 T149 MOAD: Kd=13.2uM
PDBbind-CN: -logKd/Ki=4.88,Kd=13.2uM
BS02 MG A D78 D80 D79 D81
BS03 MG A T69 D72 F74 E142 T70 D73 F75 E143
External links
PDB RCSB:6jon, PDBe:6jon, PDBj:6jon
PDBsum6jon
PubMed31176489
UniProtM5AAG8|POL_BPNNR DNA Primase-polymerase (Gene Name=28)

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