Structure of PDB 6jj9 Chain A

Receptor sequence
>6jj9A (length=465) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence]
EERRRRAAAVIEEVEQRFSTPTALLRGIADAMVEEMERGLRADPHAPLKM
LISYVDNLPTGDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVA
IPPHLMVGTSMELFDFIAAELESFVKTEGEDFHLPEGRQRELGFTFSFPV
HQTSISSGTLIKWTKGFSINGTVGEDVVAELSRAMERQGLDMKVTALVND
TVGTLAGGRYVDNDVAAAVILGTGTNAAYVEHANAIPKWTGLLPRSGNMV
INMEWGNFKSERLPRSDYDNALDFESLNPGEQIYEKMISGMYLGEIVRRI
LLKLAHDASLFGDVVPTKLEQRFILRTPDMSAMHHDTSHDLKHLGAKLKD
ILGVADTSLEARYITLHVCDLVAERGARLAAAGIYGILKKLGRDRVPSDG
SQKQRTVIALDGGLYEHYKKFRTCLEATLADLLGEEAASSVVVKLANDGS
GIGAALLAASHSQYA
3D structure
PDB6jj9 Crystal structure of OsHXK6-Glc-ATP-Mg2+ complex
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.1: hexokinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A T113 T261 T365 P366 S369 G451 L452 H455 Y456 T75 T223 T327 P328 S331 G413 L414 H417 Y418
BS02 BGC A S185 F186 T202 K203 N237 D238 N264 E292 E323 S147 F148 T164 K165 N199 D200 N226 E254 E285
Gene Ontology
Molecular Function
GO:0004340 glucokinase activity
GO:0004396 hexokinase activity
GO:0005524 ATP binding
GO:0005536 D-glucose binding
GO:0008865 fructokinase activity
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0001678 intracellular glucose homeostasis
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0009749 response to glucose
GO:0016310 phosphorylation
GO:0019318 hexose metabolic process
GO:0046835 carbohydrate phosphorylation
GO:0051156 glucose 6-phosphate metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009527 plastid outer membrane
GO:0009707 chloroplast outer membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6jj9, PDBe:6jj9, PDBj:6jj9
PDBsum6jj9
PubMed
UniProtQ8LQ68|HXK6_ORYSJ Hexokinase-6 (Gene Name=HXK6)

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