Structure of PDB 6jil Chain A

Receptor sequence
>6jilA (length=297) Species: 1914 (Streptomyces lavendulae) [Search protein sequence]
GILALVTDAVSLPIDYDMPPLLEACRTVGITAEVCDWEDGTVDWSRFEAV
VFRSPWTWAERQAEFLAFCERVSHVTRLITPMPLVRWALDKRYLADLAAH
GVPVIPTTVVAPGSDALAAVRDFLAARPEAREFVVKPTDGCYSKDVQRYQ
RSLAEPASRHVARLLANGSHVILQPYVESVDRHGETDLTFFDGVYSHAIH
KGAMLMPDGTVHVPTLDFRQARDADEDQRAVAAAALAASVAHLGLDLPLV
CGRVDLVRGADGSPMVLEMELCEPSLNLTFSEDGALRFAQALAERLK
3D structure
PDB6jil Cyclization mechanism catalyzed by an ATP-grasp enzyme essential for d-cycloserine biosynthesis.
ChainA
Resolution2.32 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.3.3.5: O-ureido-D-serine cyclo-ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A K92 K137 C142 S144 Q175 Y177 V178 E186 M205 L206 E269 K91 K136 C141 S143 Q174 Y176 V177 E185 M204 L205 E268
BS02 MG A E269 E271 E268 E270
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016882 cyclo-ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6jil, PDBe:6jil, PDBj:6jil
PDBsum6jil
PubMed31793174
UniProtD2Z030|DCSG_STRLA Cycloserine biosynthesis protein DcsG (Gene Name=dcsG)

[Back to BioLiP]