Structure of PDB 6jij Chain A

Receptor sequence
>6jijA (length=297) Species: 11142 (Murine hepatitis virus strain A59) [Search protein sequence]
SGIVKMVSPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSDMTDP
DYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYS
FGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGSVGYVL
TGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTV
NVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLVLDALA
SMTGVTVEQVLAAIKRLHSGFQGKQILGSCVFEDELTPSDVYQQLAG
3D structure
PDB6jij The crystal structure of main protease from mouse hepatitis virus A59 in complex with an inhibitor.
ChainA
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F138 G141 C143 H161 Q162 L163 E164 Q187 V188 V189 F138 G141 C143 H161 Q162 L163 E164 Q187 V188 V189
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6jij, PDBe:6jij, PDBj:6jij
PDBsum6jij
PubMed30833083
UniProtP0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab (Gene Name=rep)

[Back to BioLiP]