Structure of PDB 6jez Chain A

Receptor sequence
>6jezA (length=240) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
3D structure
PDB6jez Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I238 K242 Q255 I256 K260 P412 L413 E416 I58 K62 Q75 I76 K80 P232 L233 E236
BS02 YSV A Y143 V230 S233 R270 S271 S274 W282 C284 V296 H301 H393 Y21 V50 S53 R90 S91 S94 W102 C104 V116 H121 H213 BindingDB: Ki=0.030000nM
BS03 EJO A L136 D137 H140 K141 L14 D15 H18 K19
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:6jez, PDBe:6jez, PDBj:6jez
PDBsum6jez
PubMed31991094
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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