Structure of PDB 6j7t Chain A

Receptor sequence
>6j7tA (length=290) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
KPYSSPPTNLRSLRDRLTQVAERQGVVFGRLQRHVAMIVVAQFAATLTDD
TGAPLLLVKGGSSLELRRGIPDSRTSKDFATVARRDIELIHEQLADAGET
GWEGFTAIFTAPEEIDVPGMPVKPRRFTAKLSYRGRAFATVPIEVSSVEA
GNADQFDTLTSDALGLVGVPAAVAVPCMTIPWQIAQKLHAVTAVLEEPKV
NDRAHDLVDLQLLEGLLLDADLMPTRSACIAIFEARAQHPWPPRVATLPH
WPLIYAGALEGLDHLELARTVDAAAQAVQRFVARIDRATK
3D structure
PDB6j7t Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism.
ChainA
Resolution1.903 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A A222 L224 M225 A220 L222 M223
BS02 MG A L12 R138 L10 R136
BS03 MG A Q157 F158 Q155 F156
BS04 MG A V193 T194 V247 A248 V191 T192 V245 A246
BS05 MG A T112 A113 F129 T110 A111 F127
BS06 MG A G153 W184 G151 W182
BS07 MG A Y5 Q21 V22 R25 Y3 Q19 V20 R23
BS08 MG A T20 A23 E24 T18 A21 E22
BS09 MG A A258 E262 A256 E260
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6j7t, PDBe:6j7t, PDBj:6j7t
PDBsum6j7t
PubMed32382148
UniProtP96356

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