Structure of PDB 6j4t Chain A

Receptor sequence
>6j4tA (length=340) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
MEWIQSLPKIELHAHLNGSIRDSTLLELARVLGEKGVIVFADVEHVIQKN
DRSLVEVFKLFDLIHKLTTDHKTVTRITREVVEDFALENVVYLELRTTPK
RSDSIGMSKRSYMEAVIQGLRSVSEVDIDFVTRKKIYVRLLLSIDRRETT
ESAMETVKLALEMRDVGVVGIDLSGNPLVGEWSTFLPALQYAKDNDLHIT
LHCGEVPNPKEIQAMLDFKPHRIGHACFFKDEDWTKLKSFRIPVEICLTS
NIVTKSISSIDIHHFADLYNAKHPLILCTNDFGVFSTSLSNEYALAVRSL
GLSKSETFALARAAIDATFAEDEVKQQLRFIFDSASPEHV
3D structure
PDB6j4t Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing.
ChainA
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IMP A H15 N17 F58 F61 H65 T97 T98 K100 G190 H217 E220 D296 H15 N17 F58 F61 H65 T97 T98 K100 G175 H202 E205 D281
BS02 ZN A H13 H217 N295 H13 H202 N280
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
GO:0062154 N6-methyl-AMP deaminase activity
Biological Process
GO:0006401 RNA catabolic process
GO:0009117 nucleotide metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6j4t, PDBe:6j4t, PDBj:6j4t
PDBsum6j4t
PubMed31318636
UniProtQ8LPL7|ADAL_ARATH N6-mAMP deaminase (Gene Name=MAPDA)

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