Structure of PDB 6j4q Chain A

Receptor sequence
>6j4qA (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
FHVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQV
PNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKE
MTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGI
YCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKI
GLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKIL
3D structure
PDB6j4q Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TQ8 A Y123 C158 F191 H192 H193 S210 R211 Y75 C110 F143 H144 H145 S162 R163
BS02 TQ8 A E214 Y239 E166 Y191
Gene Ontology
Biological Process
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6j4q, PDBe:6j4q, PDBj:6j4q
PDBsum6j4q
PubMed31235911
UniProtQ86V25|VASH2_HUMAN Tubulinyl-Tyr carboxypeptidase 2 (Gene Name=VASH2)

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