Structure of PDB 6j1f Chain A

Receptor sequence

>6j1fA (length=564) Species: 224324 (Aquifex aeolicus VF5)

SHMRILFLSYRFNSLSQRLYCELTEREHEVSVELDVHPDLTVEAAELYKP
DLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWG
VTLLEASEEYDAGDVWAYRTFPMRFARKASIYRNEVTEGVVECVLEALEN
FERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGA
SSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMR
ERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIG
FIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLN
TIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGAGGVFLA
LTCDLVFAREGVVLNPHYKNIGNLYGSEFWTYTLPKRVGWEKGKEVMENR
MPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKK
KERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRRKPHFRT
PPYLAIHRRLKFSL

3D structure

• PDB: 6j1f Structural characterization of HypX responsible for CO biosynthesis in the maturation of NiFe-hydrogenase.
• Chain: A
• Resolution: 2.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	COA	A	R9 N11 S12 Q15 R131 S194 K256 N306 A308 N343 M345 L347 A392 G393 N413 I419 F539	R11 N13 S14 Q17 R133 S196 K258 N308 A310 N345 M347 L349 A394 G395 N415 I421 F541
BS02	THG	A	L56 K57 R58 K59 I60 W65 I72 P83 S105 Y108 D109 K167	L58 K59 R60 K61 I62 W67 I74 P85 S107 Y110 D111 K169

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity

Biological Process

• GO:0009058 biosynthetic process

External links

• PDB: RCSB:6j1f, PDBe:6j1f, PDBj:6j1f
• PDBsum: 6j1f
• PubMed: 31646188
• UniProt: O67224