Structure of PDB 6ixt Chain A

Receptor sequence
>6ixtA (length=405) Species: 70448 (Ostreococcus tauri) [Search protein sequence]
SKITAAPMVYVRGEEMTAYVMDLIRSRWIEPRVDVGGWETFDLRAKNRDD
TEDRVLRDVIEAGKRIKAIFKEPTVTPTADQVKRLGLRKSWGSPNGAMRR
GWNGITISRDTIHIDGVELGYKKPVLFERHAVGGEYSAGYKNVGKGKLTT
TFTPSEGPDAGKTVVVDEREIVDEEAAVVTYHNPYDNVHDLARFFFGRCL
EAKVTPYVVTKKTVFKWQEPFWQIMRTVFDEEFKAQFVAAGVMKEGEELV
HLLSDAATMKLVQWRQGGFGMAAHNYDGDVLTDELAQVHKSPGFITSNLV
GVHEDGTLIKEFEASHGTVADMDEARLRGEETSLNPLGMVEGLIGAMNHA
ADVHNIDRDRTHAFTTKMRTVIHQLFREGKGTRDLCGPSGLTTEQFIDAV
AERLD
3D structure
PDB6ixt Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.41: isocitrate dehydrogenase (NAD(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A H339 G340 V342 D344 M345 N358 H316 G317 V319 D321 M322 N335
BS02 MG A D302 D306 D279 D283
Gene Ontology
Molecular Function
GO:0004450 isocitrate dehydrogenase (NADP+) activity
Biological Process
GO:0006102 isocitrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6ixt, PDBe:6ixt, PDBj:6ixt
PDBsum6ixt
PubMed33957092
UniProtA0A096P8D3|IDH_OSTTA Isocitrate dehydrogenase (NAD(+)), mitochondrial (Gene Name=IDH)

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