Structure of PDB 6ivo Chain A

Receptor sequence
>6ivoA (length=269) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGF
RNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVA
FSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQ
LREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVAFAYTLILQRTVY
LFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDL
PLNAMCNTIERNLLDMTGQ
3D structure
PDB6ivo Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H108 H111 H88 H91
BS02 ZN A D261 D269 D241 D249
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ivo, PDBe:6ivo, PDBj:6ivo
PDBsum6ivo
PubMed31263784
UniProtW9BH30

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