Structure of PDB 6ivm Chain A

Receptor sequence
>6ivmA (length=270) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGF
RNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVA
FSWSLKHQLRKTDPTADLRRLLAEERVTEILASSMPTNRILLLAGNEIGQ
LREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVY
LFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDL
PLNAMCNTIERNLLDMTGQH
3D structure
PDB6ivm Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
ChainA
Resolution2.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H108 H111 H88 H91
BS02 ZN A D261 D269 D241 D249
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ivm, PDBe:6ivm, PDBj:6ivm
PDBsum6ivm
PubMed31263784
UniProtW9BH30

[Back to BioLiP]