Structure of PDB 6iua Chain A

Receptor sequence
>6iuaA (length=422) Species: 10090 (Mus musculus) [Search protein sequence]
NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYF
3D structure
PDB6iua Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S105 F138 W142 N146 S149 G150 T155 Q181 W184 N188 D192 W231 R238 D270 G281 N283 R315 V321 T322 W357 N361 A364 E396 W399 S31 F64 W68 N72 S75 G76 T81 Q107 W110 N114 D118 W157 R164 D196 G207 N209 R241 V247 T248 W283 N287 A290 E322 W325
External links
PDB RCSB:6iua, PDBe:6iua, PDBj:6iua
PDBsum6iua
PubMed30685087
UniProtP52293|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)

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