Structure of PDB 6isj Chain A

Receptor sequence
>6isjA (length=324) Species: 1230076 (Cryptococcus neoformans var. grubii Bt85) [Search protein sequence]
SVARVYANVNEKLGRSWWDYDNLVVQWGVQDNYEIVRKVGRGKYSEVFES
IHLPTDSKCIVKVLKKKKKIKREIKILQNLAGGPNVVGLLDVVRDSQSKT
PSIVTEYVNNTEFKTLYPKFSDFDVRYYIFELLKALDFCHSKGIMHRDVK
PHNVMIDHEKRTLRLIDWGLAEFYHPGTEYNVRVASRYFKGPELLVDFQE
YDYSLDMWSLGCMFASMIFRKEPFFHGHDNADQLVKIAKVLGTDELYTYL
ERYDIDLDAQFDDILGRYPRKPWSRFVSSENQRYISSEAIDFLDKLLRYD
HQERLTAEEAKEHPYFEPVRQAAA
3D structure
PDB6isj Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3NG A V44 G45 R46 I65 K67 V115 M162 I173 D174 V39 G40 R41 I60 K62 V108 M155 I166 D167
Gene Ontology
--> -->
 
 
UnboundLocalError		Python 3.6.8: /usr/bin/python3
Fri Nov 29 13:31:12 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)
   1444         else:
=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)
   1446     
   1447     uniprot_line=''
pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '6isj', asym_id = 'A', title = 'Unprecedented selectivity and structural determi... in clinical trials for the treatment of cancer. '
 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='6isj', asym_id='A', title='Unprecedented selectivity and structural determi... in clinical trials for the treatment of cancer. ')
    839 
    840     if go:
=>  841         display_go(go,uniprot,pdbid,asym_id)
    842     return pubmed,uniprot
    843 
global display_go = <function display_go>, go = '0004672,0004674,0005524,0006468', uniprot = '', pdbid = '6isj', asym_id = 'A'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004672,0004674,0005524,0006468', uniprot='', pdbid='6isj', asym_id='A')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>