Structure of PDB 6ir0 Chain A

Receptor sequence
>6ir0A (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
NYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKALGSLAVGHLTKCSHA
FHLLCLLAMYCNGNKDGSLQCPSCKT
3D structure
PDB6ir0 Zinc finger domain of the human DTX protein adopts a unique RING fold.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C14 C17 H52 C55 C14 C17 H52 C55
BS02 ZN A C47 H49 C71 C74 C47 H49 C71 C74
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0016567 protein ubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:6ir0, PDBe:6ir0, PDBj:6ir0
PDBsum6ir0
PubMed30927328
UniProtQ86UW9|DTX2_HUMAN Probable E3 ubiquitin-protein ligase DTX2 (Gene Name=DTX2)

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