Structure of PDB 6iod Chain A

Receptor sequence
>6iodA (length=212) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
GSHMAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARI
MMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFK
FTRAAGGKRRIHKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKAL
LGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGL
VDDLRVAADVRP
3D structure
PDB6iod Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Q53 P68 A69 H109 G140 A141 R153 V154 T155 V177 H178 S180 S181 L183 R184 Q56 P71 A72 H112 G143 A144 R156 V157 T158 V180 H181 S183 S184 L186 R187
BS02 SF4 A C24 G26 C27 K94 H95 C120 W123 C27 G29 C30 K97 H98 C123 W126
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0097506 deaminated base DNA N-glycosylase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function

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Biological Process
External links
PDB RCSB:6iod, PDBe:6iod, PDBj:6iod
PDBsum6iod
PubMed31101915
UniProtI7F541

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