Structure of PDB 6imj Chain A

Receptor sequence
>6imjA (length=412) Species: 10497 (African swine fever virus) [Search protein sequence]
MLNQFPGQYSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDEM
FSTDVKDAVAEIFTKFFVEEGAVRISKMTRVTEGKNLGKKNATTVVHQAF
KDALSKYNRHARQKRRGMIPPMLVKYFNIIPKTFFEEETDPIVQRKRNGV
RAVACQQGDGCILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELY
LHRKPLQWIAGQANAKTDSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIF
KQKEDLTFIHQVENFSVKNVDEALRLKAQFIKEGYEGAIVRNANGPYEPG
YNNYHSAHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKKRFV
VTPKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPGIPLQARAV
GFREPINVLEII
3D structure
PDB6imj Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues.
ChainA
Resolution2.554 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R74 K85 N86 S105 R74 K85 N86 S105
BS02 dna A W31 K89 N91 K106 R109 H110 K185 W31 K89 N91 K106 R109 H110 K180
BS03 ATP A L128 V129 Q149 R150 K151 R152 R156 R172 E203 F232 I294 R296 K316 L123 V124 Q144 R145 K146 R147 R151 R167 E198 F227 I289 R291 K311
Gene Ontology
Molecular Function
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0051301 cell division
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6imj, PDBe:6imj, PDBj:6imj
PDBsum6imj
PubMed30674878
UniProtP35970|DNLI_ASFB7 DNA ligase (Gene Name=LIG)

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