Structure of PDB 6iiy Chain A

Receptor sequence
>6iiyA (length=237) Species: 1867 (Actinoplanes teichomyceticus) [Search protein sequence]
TRLLAISPHLDDAVLSFGAGLAQAAQDGANVLVYTVFAGAAQPPYSPAAQ
RMHTIWGLAPDDDAVLYRRKEDIAALDHLRVAHRHGRFLDAIYRHDLVGE
VADDIRSIIDEFDPTLVVTCAAIGEHPDHEATRDAALFATHEKNVPVRLW
EDLPYAVYKGAVELPQGFRLGSADVSSVKPEMRSQKFQAVERYSSQMVLL
NGSENNLFDRLDEHARQNAPHGGYGETTWPVVRSDDS
3D structure
PDB6iiy Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens.
ChainA
Resolution1.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CO A H16 D19 H164 H9 D12 H129
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016137 glycoside metabolic process

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6iiy, PDBe:6iiy, PDBj:6iiy
PDBsum6iiy
PubMed30599088
UniProtQ6ZZJ1

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