Structure of PDB 6iie Chain A

Receptor sequence
>6iieA (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
PEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPIL
QEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLE
3D structure
PDB6iie Crystal structure and calcium-induced conformational changes of diacylglycerol kinase alpha EF-hand domains.
ChainA
Resolution2.142 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.107: diacylglycerol kinase (ATP).
2.7.1.93: alkylglycerol kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D123 D125 N127 I129 E134 D13 D15 N17 I19 E24
BS02 CA A D168 D170 S172 S174 E179 D58 D60 S62 S64 E69
BS03 GOL A Q141 Y148 Q31 Y38
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6iie, PDBe:6iie, PDBj:6iie
PDBsum6iie
PubMed30653270
UniProtP23743|DGKA_HUMAN Diacylglycerol kinase alpha (Gene Name=DGKA)

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