Structure of PDB 6iez Chain A

Receptor sequence
>6iezA (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
THRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGI
VLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAI
IIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAP
LNNRCVRAKINVAMICQTLVSEISRDNILCKITYVANVNPGGWAPASVLR
AVAKREYPKFLKRFTSYVQEKTAGKPILF
3D structure
PDB6iez Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A50 A F436 E446 H469 V472 V525 Y553 V557 V571 E575 Y576 F73 E83 H106 V109 V162 Y184 V188 V202 E206 Y207 PDBbind-CN: -logKd/Ki=6.52,Kd=0.3uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6iez, PDBe:6iez, PDBj:6iez
PDBsum6iez
PubMed
UniProtQ9Y5P4|CERT_HUMAN Ceramide transfer protein (Gene Name=CERT1)

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