Structure of PDB 6iej Chain A

Receptor sequence
>6iejA (length=126) Species: 9031 (Gallus gallus) [Search protein sequence]
SYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFN
NDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKL
GEKKEVQLTFNNVTEMTLELSLEVCS
3D structure
PDB6iej Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
ChainA
Resolution2.206 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.4: phospholipase A2.
3.1.1.5: lysophospholipase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D40 D43 D93 A94 N95 D26 D29 D79 A80 N81
BS02 CA A D40 T41 D43 N65 D26 T27 D29 N51
BS03 MG A D66 N68 D52 N54
BS04 HXG A L39 D43 H62 N64 N65 N95 Y96 L25 D29 H48 N50 N51 N81 Y82
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0008289 lipid binding

View graph for
Molecular Function
External links
PDB RCSB:6iej, PDBe:6iej, PDBj:6iej
PDBsum6iej
PubMed31050338
UniProtP49147|PA24A_CHICK Cytosolic phospholipase A2 (Gene Name=PLA2G4A)

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