Structure of PDB 6icl Chain A

Receptor sequence
>6iclA (length=338) Species: 303 (Pseudomonas putida) [Search protein sequence]
KPLLEDKTYLRHFWHPVCTLNEFERANASGHGPMGVTLLGEKLVLARLNS
KIIAAADRCAHRSAQLSIGRVCSNAGKDYLECPYHGWRYDEAGACQLIPA
CPDKSISPRAKISSFDCEVKYDIVWVRLDNSFDCTQIPYLSDFDNPDMQV
IVADSYIWETVAERRWENFTDFSHFAFVHPGTLYDPFFASHPTVYVNRVD
GELQFKLAPPPMGDFTYRCTMPYSVNLEIKLWKDDSRFVLWTTASPVDNK
SCRNFMIIVREKDNQPDHMHLAFQKRVLDEDQPVIESQWPLEIQTSEVSV
ATDKISVQFRKWHKELSLSAVEGREAFRDSVLTNVIEE
3D structure
PDB6icl Structural and Mechanistic Insights into Caffeine Degradation by the Bacterial N-Demethylase Complex.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.179: methylxanthine N(3)-demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES A C64 H66 R67 A69 C87 Y89 H90 W92 C59 H61 R62 A64 C82 Y84 H85 W87
BS02 FE A H179 H184 D296 H174 H179 D281
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0032451 demethylase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0009820 alkaloid metabolic process
GO:0009822 alkaloid catabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6icl, PDBe:6icl, PDBj:6icl
PDBsum6icl
PubMed31412262
UniProtH9N290|NDMB_PSEPU Methylxanthine N3-demethylase NdmB (Gene Name=ndmB)

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