Structure of PDB 6i8y Chain A

Receptor sequence
>6i8yA (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
RNIVGCRIQHGWKEGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGL
ELNKDERVSALEVLPDRVALADTMIGKAVEHMFETEDGSKDEWRGMVLAR
APVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPSLVGKQVEYAKKRT
GMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTSAENLYFQ
3D structure
PDB6i8y A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
ChainA
Resolution1.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2OD A H139 F141 W151 Y170 Y179 D184 H81 F83 W93 Y112 Y121 D126 BindingDB: Kd=110nM,IC50=186nM
BS02 2OD A W62 W72 Y91 F94 Y98 F251 W12 W22 Y41 F44 Y48 F172 BindingDB: Kd=110nM,IC50=186nM
Gene Ontology
Biological Process
GO:0007276 gamete generation

View graph for
Biological Process
External links
PDB RCSB:6i8y, PDBe:6i8y, PDBj:6i8y
PDBsum6i8y
PubMed31550156
UniProtQ9Y657|SPIN1_HUMAN Spindlin-1 (Gene Name=SPIN1)

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