Structure of PDB 6i78 Chain A

Receptor sequence
>6i78A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB6i78 Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 H5H A R144 H158 N160 R162 N174 W181 E184 R32 H46 N48 R50 N62 W69 E72 MOAD: Kd=18uM
PDBbind-CN: -logKd/Ki=4.74,Kd=18uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:6i78, PDBe:6i78, PDBj:6i78
PDBsum6i78
PubMed30632578
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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