Structure of PDB 6i64 Chain A

Receptor sequence
>6i64A (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
YNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWA
KHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMD
EDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQ
HFYNIKLEGKVPMHKLFLEMLEAK
3D structure
PDB6i64 Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors.
ChainA
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 H48 A E275 M306 L309 Y326 N346 I349 F435 E42 M73 L76 Y93 N113 I116 F202 MOAD: Kd=48.7nM
PDBbind-CN: -logKd/Ki=7.31,Kd=48.7nM
External links
PDB RCSB:6i64, PDBe:6i64, PDBj:6i64
PDBsum6i64
PubMed31127318
UniProtP62508|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)

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