Structure of PDB 6i5p Chain A

Receptor sequence
>6i5pA (length=136) Species: 9606 (Homo sapiens) [Search protein sequence]
VVKFSYMWTINNFSFCREKMGEVIKSSTFSSGANDKLKWCLRVNPKGLDE
ESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQG
KDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVV
3D structure
PDB6i5p Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
ChainA
Resolution1.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y87 K129 D130 W131 G132 F133 K134 Y59 K101 D102 W103 G104 F105 K106
External links
PDB RCSB:6i5p, PDBe:6i5p, PDBj:6i5p
PDBsum6i5p
PubMed31026449
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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