Structure of PDB 6i4x Chain A

Receptor sequence
>6i4xA (length=158) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSD
YLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSALAAFDSVVHLIDYY
VQMCKDKVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDY
LEEYKFQV
3D structure
PDB6i4x Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
ChainA
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R73 S75 S76 T83 T93 N94 L95 R96 D107 S108 I109 R44 S46 S47 T54 T64 N65 L66 R67 D78 S79 I80
Gene Ontology
Biological Process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:6i4x, PDBe:6i4x, PDBj:6i4x
PDBsum6i4x
PubMed31182716
UniProtO14508|SOCS2_HUMAN Suppressor of cytokine signaling 2 (Gene Name=SOCS2)

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