Structure of PDB 6i4g Chain A

Receptor sequence
>6i4gA (length=356) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
VQALVVDNGSGNVKAGVAGDDAPRSVFPSIVGRPAFVGDEAQTKRGILTL
KYPIEQGIVTNWDDMEKIWHHTFYNELRAAPEEHPVLLTEAPLNPKGNRE
RMTQIMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLDSGDGVSHTVPIYE
GYALPHAIMRLDLAGRDLTEYLMKILHERGYGFSTSAEKEIVRDIKEKLC
YIALNFDEEMKTSEQSSDIEKSYELPDGNIITVGNERFRCPEALFQPSFL
GKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLSGGTTMYEGIGERLTRDI
TTLAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQMWITKEEYDESGP
SIVHRK
3D structure
PDB6i4g Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G14 S15 G16 K19 G157 D158 V160 K214 E215 G303 M306 Y307 K337 G9 S10 G11 K14 G139 D140 V142 K196 E197 G285 M288 Y289 K319
BS02 K A D155 S156 G157 V160 S161 D137 S138 G139 V142 S143
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0007010 cytoskeleton organization
GO:0009665 plastid inheritance
GO:0020014 schizogony
GO:0070360 symbiont-mediated actin polymerization-dependent cell-to-cell migration in host
GO:0085017 entry into host cell by a symbiont-containing vacuole
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6i4g, PDBe:6i4g, PDBj:6i4g
PDBsum6i4g
PubMed31199804
UniProtQ8I4X0|ACT1_PLAF7 Actin-1 (Gene Name=ACT1)

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