Structure of PDB 6i41 Chain A

Receptor sequence
>6i41A (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
SGKVVKFSYMWTINNFSFCREGEVIKSSTFSSGANDKLKWCLRVNPKGLD
EESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQ
GKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQD
3D structure
PDB6i41 Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y87 Y123 K129 D130 W131 G132 F133 K134 Y60 Y96 K102 D103 W104 G105 F106 K107
External links
PDB RCSB:6i41, PDBe:6i41, PDBj:6i41
PDBsum6i41
PubMed31026449
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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