Structure of PDB 6i1e Chain A

Receptor sequence
>6i1eA (length=515) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
PARSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQ
LAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSI
EEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKD
RRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGS
LVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKP
FSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIK
SSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWP
KAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQV
ISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGY
RENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAG
ALRLMNVPPDNLPTA
3D structure
PDB6i1e Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
ChainA
Resolution1.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AXL A S294 V333 S349 N351 Y409 S485 G486 T487 Y532 F533 S246 V285 S301 N303 Y361 S437 G438 T439 Y484 F485
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008658 penicillin binding
GO:0008955 peptidoglycan glycosyltransferase activity
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0000917 division septum assembly
GO:0006508 proteolysis
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0043093 FtsZ-dependent cytokinesis
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6i1e, PDBe:6i1e, PDBj:6i1e
PDBsum6i1e
PubMed31301409
UniProtG3XD46|FTSI_PSEAE Peptidoglycan D,D-transpeptidase FtsI (Gene Name=ftsI)

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