Structure of PDB 6i0u Chain A

Receptor sequence
>6i0uA (length=350) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
QAQVKARQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIE
QDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEH
RASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDI
CLNSMGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITL
MVIYFLQLQALLPPIAMLQIEQAVLVGPWVVNFAQKSFSELGLQQLKATV
PVIKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYV
SDNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLE
3D structure
PDB6i0u Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
ChainA
Resolution2.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A F265 D278 D280 I323 Q325 A326 R327 V328 D343 N353 Y390 F71 D84 D86 I129 Q131 A132 R133 V134 D149 N159 Y196
BS02 MG A D278 D280 D84 D86
BS03 MG A D278 D280 D343 D84 D86 D149
External links
PDB RCSB:6i0u, PDBe:6i0u, PDBj:6i0u
PDBsum6i0u
PubMed30462292
UniProtQ9VI58|TUTT_DROME Terminal uridylyltransferase Tailor (Gene Name=Tailor)

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