Structure of PDB 6hy1 Chain A

Receptor sequence
>6hy1A (length=281) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDG
VIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSV
ENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTY
DVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTI
KNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLES
KEFADLKYYNYENHSAAFKLPAFLLKEIENI
3D structure
PDB6hy1 Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N,N'-Bis(3-aminopropyl)-1,4-cyclohexanediamine after catalysis in crystal
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GXQ A W51 Q93 H103 D127 D196 D199 E231 Y264 W11 Q53 H63 D87 D156 D159 E191 Y224
BS02 MTA A G124 G125 D127 E147 I148 V152 D178 A179 S198 P203 A204 L207 G84 G85 D87 E107 I108 V112 D138 A139 S158 P163 A164 L167
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:6hy1, PDBe:6hy1, PDBj:6hy1
PDBsum6hy1
PubMed
UniProtQ8II73

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