Structure of PDB 6hxp Chain A

Receptor sequence
>6hxpA (length=256) Species: 940 (Hydrogenobacter thermophilus) [Search protein sequence]
RIWKTGITQHIGHETYIRGYRLLDLVGNLSFAQAIYLILKGELPTERESR
MMEAMLVSVIDHGIAPPSAIAARSVASGGNSLNVGVAAGVLAFGSAHGGA
LEDAMRFIQEGVSSKRSVEDIVKEYLETKKPIPGYGHRYYKDFDPRTKRL
MDIARVLEFYGEHCKFAEDVAEEIGRQKGKKLVLNVDGAIAAIASEMGFD
WRLGKGFFIIGRVPGLVAHVYEELTTEKPFSKRLDEERDVEYTGSPPREL
PQELKK
3D structure
PDB6hxp Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.3.16: citrate synthase (unknown stereospecificity).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A D105 I134 P135 Y137 G138 K143 K180 K182 L184 D103 I132 P133 Y135 G136 K141 K178 K180 L182
Gene Ontology
Molecular Function
GO:0004108 citrate (Si)-synthase activity
GO:0016829 lyase activity
GO:0036440 citrate synthase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6hxp, PDBe:6hxp, PDBj:6hxp
PDBsum6hxp
PubMed30944476
UniProtQ75VX1

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