Structure of PDB 6hws Chain A

Receptor sequence
>6hwsA (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLL
YAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYA
VGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGG
YDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDG
HTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB6hws Keap1-inhibitor complex
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GX8 A Y334 N414 R415 R483 S508 Y525 Q530 S555 A556 Y572 F577 Y10 N90 R91 R159 S184 Y201 Q206 S231 A232 Y248 F253
External links
PDB RCSB:6hws, PDBe:6hws, PDBj:6hws
PDBsum6hws
PubMed
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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