Structure of PDB 6hvd Chain A

Receptor sequence
>6hvdA (length=286) Species: 9606 (Homo sapiens) [Search protein sequence]
MKQYEHVTRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDT
KSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVD
AVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDG
DIKLADFGVSAKNTRSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI
TLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCL
EKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKA
3D structure
PDB6hvd Human SLK bound to a maleimide inhibitor
ChainA
Resolution1.63 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D155 K157 G159 N160 D173 R182 T193
Catalytic site (residue number reindexed from 1) D138 K140 G142 N143 D156 R165 T170
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GUQ A L40 G41 D42 V48 A61 I108 F110 L162 D173 L23 G24 D25 V31 A44 I91 F93 L145 D156
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6hvd, PDBe:6hvd, PDBj:6hvd
PDBsum6hvd
PubMed
UniProtQ9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase (Gene Name=SLK)

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