Structure of PDB 6huy Chain A

Receptor sequence

>6huyA (length=350) Species: 868864 (Desulfurobacterium thermolithotrophum DSM 11699) [Search protein sequence]

MRVTVYGFGSLNYYSNKLNVPEKLGGEPPYGGSAMAVEFAKAGHDVTLSD
PNIDKVPDEIRKKVEDAGVKLTTDDIEAAKEAEVAILFTPFRGGVTFKIA
ETILPYLVENAVICTTCTMSILVLNSYLQNAIFLEGREDIGFSTMHPAAI
PGTPQHKHYLIATNELLRKPIVTEEQIEKLKKLATDTGKEAYLLPAELVS
PVGDMGIVTTAIAFAGAIEYYKVSRDILKTKRSMTEFQIAQSLQVISSLV
TKYGLEGLIKLLNVDAMKASLQSMILDKNEQPLTVTASKLLEKIEETIPE
LIKEAENFSPSEPTYTSAPSPMLVEHMEDLVGDDVLKGILRESWKKFYEN

3D structure

PDB

6huy The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates.

Chain

Resolution

2.25 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.12.98.2: 5,10-methenyltetrahydromethanopterin hydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	FE9	A	G9 S10 Y14 S49 D50 P51 D75 F88 T89 P90 I99 T116 C117 T118 P147 A149	G9 S10 Y14 S49 D50 P51 D75 F88 T89 P90 I99 T116 C117 T118 P147 A149
BS02	GUE	A	Y13 K17 F91 R92 A148 I150 G203 D204 M205	Y13 K17 F91 R92 A148 I150 G203 D204 M205
BS03	GUE	A	T230 M234 S270 S273 M274	T230 M234 S270 S273 M274

External links

PDB	RCSB:6huy, PDBe:6huy, PDBj:6huy
PDBsum	6huy
PubMed	30600878
UniProt	F0S2B6

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