Structure of PDB 6ht1 Chain A

Receptor sequence
>6ht1A (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]
DNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKV
VFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFT
YDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVM
3D structure
PDB6ht1 Discovery of an MLLT1/3 YEATS Domain Chemical Probe.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GQ5 A F28 H56 S58 F59 P60 E75 S76 G77 Y78 A79 G80 F27 H55 S57 F58 P59 E74 S75 G76 Y77 A78 G79 MOAD: Kd=0.077uM
PDBbind-CN: -logKd/Ki=7.11,Kd=0.077uM
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6ht1, PDBe:6ht1, PDBj:6ht1
PDBsum6ht1
PubMed30288907
UniProtQ03111|ENL_HUMAN Protein ENL (Gene Name=MLLT1)

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